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Discovery of Eco-compatible Synthetic Paths by a Multi-catalysis Approach- Young Carreer Focus


Description : This article summarizes our recent developments in the discovery of multi-catalytic reactions. By efficiently taking the best from different worlds, the combination of several catalytic principles allows the invention of eco-compatible transformations rapidly assembling simple building blocks into elaborated enantioenriched molecules. This type of approach was successfully illustrated in the synthesis of cyclohexenones, keto-diols or in the direct functionalization of allylic alcohols by an enantioselective borrowing hydrogen. In addition, mechanistic understanding of the role of the different constituents enabled the fine-tuning of the catalytic systems considerably improving the efficiency notably in terms of enantiocontrol.
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Contributeur : Gaelle Chouraqui <>
Soumis le : lundi 8 octobre 2018 - 15:30:01
Dernière modification le : jeudi 23 janvier 2020 - 18:22:05
Archivage à long terme le : mercredi 9 janvier 2019 - 15:22:19