Straightforward Access to a Great Diversity of Complex Biorelevant γ-Lactams Thanks to a Tunable Cascade Multicomponent Process

Muhammad Idham Darussalam Mardjan (1) , Atef Mayooufi (2) , Jean-Luc Parrain (1) , Jérôme Thibonnet (2) , Laurent Commeiras (1)

1 ISM2 - Institut des Sciences Moléculaires de Marseille
2 SIMBA - Synthèse et isolement de molécules bio-actives

The current article reviews the preparation of a great diversity of complex biorelevant γ-lactams backbones thanks to scalable copper(I)-catalyzed cascade multicomponent processes.

Mots clés: Lactams; Copper Catalysis; Heterocyclic Compounds; Multicomponent Reaction; -Hydroxybutyrolactams; Spirolactams

Domaines: Chimie organique

Muhammad Idham Darussalam Mardjan, Atef Mayooufi, Jean-Luc Parrain, Jérôme Thibonnet, Laurent Commeiras. Straightforward Access to a Great Diversity of Complex Biorelevant γ-Lactams Thanks to a Tunable Cascade Multicomponent Process. Illustration. France. 2020. ⟨hal-02873547⟩