OrthoInspector 2.0: Software and database updates

Benjamin Linard (1) , Alexis Allot (2) , Raphaël Schneider (2) , Can Morel (2) , Raymond Ripp (2) , Marc Bigler (2) , Julie D Thompson (2) , Olivier Poch (2) , Odile Lecompte (2)

1 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire
2 ICube - Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie

We previously developed OrthoInspector, a package incorporating an original algorithm for the detection of orthology and inpar-alogy relations between different species. We have added new functionalities to the package. While its original algorithm was not modified, performing similar orthology predictions, we facilitated the prediction of very large databases (thousands of proteomes), refurbished its graphical interface, added new visualization tools for comparative genomics/protein family analysis and facilitated its deployment in a network environment. Finally, we have released three online databases of precomputed orthology relationships. Availability: Package and databases are freely available at http://lbgi. fr/orthoinspector with all major browsers supported.

Domaines: Bio-informatique [q-bio.QM]; Biodiversité et Ecologie; Systématique, phylogénie et taxonomie; Génomique, Transcriptomique et Protéomique [q-bio.GN]

Benjamin Linard, Alexis Allot, Raphaël Schneider, Can Morel, Raymond Ripp, et al.. OrthoInspector 2.0: Software and database updates. Bioinformatics, 2015, 31 (3), pp.447-448. ⟨10.1093/bioinformatics/btu642⟩. ⟨hal-01636893⟩